HomeKnowPlanGoStoriesTelehealth Services
Know Plan Go

Know if you have a high-risk factor for severe COVID-19.
Be ready with a plan. And, if you have COVID-19, act fast.

Watch video
Close Loading
Many people have a high-risk factor for severe COVID-19. Some want to share their experience.  Listen to their stories
High-risk factors can increase your chances of getting very sick from COVID-19.1 That's why setting a plan now and acting fast if you test positive or if you’re feeling COVID-19 symptoms is important.1

Roughly 3 in 4 adult Americans are at high risk of becoming very sick from COVID-19.2 Are you one of them?

What’s your risk?

Mapping out a plan with your healthcare professional before COVID-19 strikes is one of the most important steps you can take to help prevent serious illness.1

Make a plan

Have COVID-19? It's time for action! Speak with your healthcare professional about whether a prescription treatment option is right for you.

Take action

Being at high risk for severe COVID-19 is more common than you think. In fact, nearly 200 million American adults have at least one risk factor that places them at high risk for getting very sick from COVID-19.2 And for people who are at high risk, symptoms that begin mild can quickly become severe.3 Unfortunately, many don't consider themselves at high risk or don't think serious illness or hospitalization could happen to them.4

Being age 50 years or older, having diabetes, or having chronic lung conditions like asthma are just some high-risk factors that can lead to severe illness, and even hospitalization, from a COVID-19 infection. Other risk factors, like being a current or former smoker, having depression, or being overweight, may surprise you.5

According to the Centers for Disease Control and Prevention, having one or more of the following factors puts you at high risk of getting severe COVID-195:
  • Age 50 years or older
  • Cancer
  • Chronic kidney disease
  • Chronic liver disease
  • Chronic lung diseases
  • Cystic fibrosis
  • Dementia or other neurological conditions
  • Diabetes (Type 1 or Type 2)
  • Disabilities
  • Heart conditions
  • HIV infection
  • Immunocompromised condition or weakened immune system
  • Mental health conditions
  • Obesity or being overweight
  • Physical inactivity
  • Pregnancy or recent pregnancy
  • Sickle cell disease or thalassemia
  • Smoking, current or former
  • Solid organ or blood stem cell transplant
  • Stroke or cerebrovascular disease
  • Substance use disorders
  • Tuberculosis

In addition to certain medical conditions, being unvaccinated or not being up to date on COVID-19 vaccinations also increases the risk of severe COVID-19 outcomes.6 Some people are also at risk of getting very sick or dying from COVID-19 because of where they live or work, or because they can’t get healthcare. This includes many people from racial and ethnic minority groups and people with disabilities.

The list above does not include all possible conditions that may put you at high risk of severe illness from COVID-19. If you have questions about a condition not included on this list, talk to your healthcare professional.

Visit the CDC website for the latest information and the full list of high-risk factors.

Unsure whether you are at high risk for severe COVID-19?

In addition to speaking with your healthcare professional for confirmation, fill out this easy-to-use questionnaire to find out if you may be at high risk for COVID-19 becoming severe, and assess if a prescription treatment option might be right for you.

Assess your riskLoading

As soon as you know that you or a loved one are at high risk of becoming very sick from COVID-19, talk to your healthcare professional about steps you can take in case of an infection. An action plan is key if you test positive or are feeling COVID-19 symptoms. When you’re prepared, you can act fast.

First, make sure your vaccinations are up to date, in accordance with CDC guidelines. Visit to schedule an appointment. The risk of hospitalization is greater in those that are not up to date on their COVID-19 vaccinations.6

You know your health situation best and that will inform how you make a personalized list of to-dos. If you test positive or are feeling COVID-19 symptoms, your plan will remind you of the steps to take right away. Some starter suggestions are listed below that you may find helpful.

  • Know how to get in touch with people you've been in contact with, who may have been exposed to the virus (SARS-CoV-2).
  • Familiarize yourself with CDC guidelines for isolation and know where you would stay, if needed, ahead of time.
  • Make sure you have enough masks on hand.
  • Also have enough at-home COVID-19 test kits and know how to get more.
  • Set a plan with loved ones so everyone knows what steps to take if anyone tests positive.
  • Keep an up-to-date list of any medications you take, including vitamins and supplements, and be ready to share with your healthcare professional.
  • Know how to quickly reach your healthcare professional if you’re feeling COVID-19 symptoms, or if you test positive, and ask whether a prescription treatment option might be right for you. 
  • Find a close and convenient location to get any necessary prescriptions, if appropriate.
  • Have someone you can turn to who can pick up items you may need during the quarantine period.

And lastly, encourage loved ones to make their own COVID-19 plan. Because nothing is more important than your family’s health.

Let’s get your plan in order

This form can act as a handy checklist if you get COVID-19. Fill it out now and use it to discuss with your healthcare professional whether a prescription for a COVID-19 treatment may be right for you.

Access the checklistLoading

It can be overwhelming if you’re feeling COVID-19 symptoms or if you test positive. Speak with your healthcare professional about whether a prescription treatment option is right for you.

You’re already aware of whether you have any high-risk factors and you’ve prepared for this moment. You’re ready to act right away.

Your healthcare professional is the go-to person to work with in this situation. They will consider your high-risk factor(s), along with your medical history and current medications, in determining whether a prescription treatment option is right for you. Remember, being at high risk means timing is everything: Since mild symptoms can quickly become severe, it's important to act by starting a treatment, if prescribed, within days of getting COVID-19.1

There are convenient locations across the U.S. where you can be tested, talk to a healthcare professional, and if appropriate, be prescribed treatment for COVID-19. Find a location near you.

It’s understandable if you feel concerned, scared, or upset if you’re feeling COVID-19 symptoms or test positive. But having your pre-planned, personalized action plan is a great way to push through that difficult time. Act decisively to help keep you and your loved ones safe.

Stick to the strategy that you created with your healthcare professional to help reduce the chance of serious illness and hospitalization from COVID-19.1

Reach out to a healthcare professional

If you do not have a healthcare professional or your healthcare professional is not available, telehealth services are a convenient way to connect with one by phone, chat, or video.

Schedule a telehealth visitLoading

Their Stories

P!NK, Questlove, Jean Smart, and Michael Phelps all have at least one high-risk factor for severe COVID-19. See what they have to say about the importance of being prepared with a plan in case the virus strikes.

See P!NK’s story

Button Loading


Award-winning singer, gifted songwriter, and trailblazing artist

See Questlove’s story

Button Loading


Award-winning filmmaker, drummer, DJ, and author

See Jean’s story

Button Loading

Jean Smart

Award-winning television, theater, and film actress

See Michael’s story

Button Loading

Michael Phelps

Dad, husband, decorated athlete, and mental health advocate

Be ready. Have a plan.

It’s important to Know Plan Go if you’re at high risk for severe COVID-19. Find out why from some people who speak from experience.

Watch video Loading
Button Loading
Close Loading
Telehealth Services

There are different ways to receive the care that you need by a healthcare professional. You can always visit one in person, or you can use telehealth, which enables care without requiring a visit to the office. With telehealth, you don’t have to travel or sit in a waiting room when you’re sick, and you can opt for an appointment that fits into your schedule.

There are many options for accessing telehealth. Explore the options below to connect virtually with a healthcare professional to discuss your care and a potential treatment plan.

Amazon Clinic  
Visit website
Visit website
CVS Minute Clinic 
Visit website
Visit website
Visit website
Visit website
SteadyMD, available through Ada 
Visit website

Pfizer does not own or operate any of these telehealth platforms or the services they or their healthcare professionals may furnish, and Pfizer accepts no responsibility or liability for them.

The above links are provided as a resource to our visitors and do not imply an endorsement or recommendation of a particular telehealth professional by Pfizer nor an endorsement of any Pfizer product by a company, healthcare professional, or platform.

Healthcare professionals or telehealth companies do not pay a fee to Pfizer for inclusion on this website.

If these telehealth platforms match users with healthcare professionals, the selection of a particular healthcare professional is determined by the criteria set by the platform and/or healthcare professional, not Pfizer. All treatment decisions are at the sole discretion of the healthcare professional based on the patient’s individual needs and risk-benefit profile.

Know Plan Go Resources
Schedule a vaccine appointment
Learn more
High-risk factors that can lead to severe COVID-19
Learn more
Where to find testing and treatment
Learn more
References: 1 Factors that affect your risk of getting very sick from COVID-19. Centers for Disease Control and Prevention. Updated February. 10, 2023. Accessed March 10, 2023. 2 Ajufo E, Rao S, Navar AM, Pandey A, Ayers CR, Khera A. U.S. population at increased risk of severe illness from COVID-19. Am J Prev Cardiol. 2021;6:100156. DOI: 10.1016/j.ajpc.2021.100156. 3 Clinical care quick reference for COVID-19. Centers for Disease Control and Prevention. Updated March 16, 2022. Accessed January 3, 2023. 4 Pfizer Research: US Consumer ATU Report Data & Analysis. January 2023. 5 People with certain medical conditions. Centers for Disease Control and Prevention. Updated February 10, 2023. Accessed March 10, 2023. 6 Havers FP, Pham H, Taylor CA, et al. COVID-19-associated hospitalizations among vaccinated and unvaccinated adults 18 years or older in 13 US states, January 2021 to April 2022. JAMA Intern Med. 2022;182(10):1071–1081. doi:10.1001/jamainternmed.2022.4299. Home Loading Know Loading Plan Loading Go Loading Stories Loading Telehealth Services Loading

This site is sponsored by Pfizer and intended for U.S. residents. The information provided is for educational purposes only and is not intended to replace discussions with a healthcare professional.

Pfizer-logo© Pfizer Inc. All rights reserved. PP-CPI-USA-0813. June 2023